Anti-CD34 antibody [2-E9]

Anti-CD34 antibody [2-E9]

• 概述

• 产品描述CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC.
• 产品名称Anti-CD34 antibody [2-E9]
• 分子量100kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC,IHC-P
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane
• 其它名称
  • CD34 antibody
  • CD34 antigen antibody
  • CD34 molecule antibody
  more

• 应用

  IHC-P: 1:200-1:500
  WB: 1:500

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  Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD34 mouse mAb.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- CD34 mouse mAb.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti- CD34 mouse mAb.

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