Anti-Reg IV antibody
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概述
- 产品描述May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum. online information:Regenerating protein IV,Contains 1 C-type lectin domain. tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
- 产品名称Anti-Reg IV antibody
- 种属反应性Human
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human Reg IV.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- REG4 antibody; GISP antibody; RELP antibody; Regenerating islet-derived protein 4 antibody; REG-4 antibody; Gastrointestinal secretory protein antibody; REG-like protein antibody; Regenerating islet-derived protein IV antibody; Reg IV antibody;
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Fig1: Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min).
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