Anti-N-Cadherin antibody [A10-4]

Anti-N-Cadherin antibody [A10-4]

• 概述

• 产品描述The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events. The cadherin subfamily includes N-, P-, B-, and E- cadherins, and other members. Recent studies indicate that cancer cells have up-regulated N-cadherin in addition to loss of E-cadherin. This change in cadherin expression is called the "cadherin switch". N-cadherin cooperates with the FGF receptor, leading to overexpression of MMP-9 and cellular invasion.
• 产品名称Anti-N-Cadherin antibody [A10-4]
• 分子量140 kDa
• 种属反应性Human,Mouse
• 验证应用WB,ICC,IHC-P
• 抗体类型小鼠单抗
• 免疫原recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• 亚型IgM
• 纯化方式Protein A purified.
• 亚细胞定位Cell membrane
• 其它名称
  • CADH2_HUMAN antibody
  • Cadherin 2 antibody
  • Cadherin 2 N cadherin neuronal antibody
  more

• 应用

  WB: 1:1,000-1:2,000
  ICC: 1:500
  IHC-P: 1:100

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  Fig1: Western blot analysis on mouse heart (1) and human heart (2) lysates using anti-N-Cadherin mouse mAb.

   

  

  Fig2: Immunofluorescent staining of A549 cells using anti-N-Cadherin mouse mAb.

   

  

  Fig3: Immunohistochemical analysis of paraffin- embedded human lung cancer tissue using anti-N-Cadherin mouse mAb.

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！