Anti-Cytokeratin 6 antibody [4A1]
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概述
- 产品描述The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathoge
- 产品名称Anti-Cytokeratin 6 antibody [4A1]
- 分子量56-60 kDa
- 种属反应性Human
- 验证应用WB,IHC-P,IF
- 抗体类型小鼠单抗
- 免疫原Synthetic Peptide of Cytokeratin 6
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
- 纯化方式Immunogen affinity purified.
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应用
WB: 1:1000
IF: 1:200
IHC-P: 1:50-300
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