Anti-FGF21 antibody [AH21-71]
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概述
- 产品描述Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
- 产品名称Anti-FGF21 antibody [AH21-71]
- 分子量22 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用ELISA,WB,ICC,IHC-P
- 抗体类型小鼠单抗
- 免疫原recombinant protein
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度2 mg/mL.
- 存放说明Store at -20 ℃. Stable for 12 months from date of receipt.
- 存储缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.10% Sodium Azide.
- 亚型IgG1
- 亚细胞定位Secreted.
- 其它名称
- FGF 21 antibody
- FGF-21 antibody
- Fgf21 antibody
more
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应用
WB: 1:1,000
ICC: 1:50-1:200
IHC-P: 1:50-1:200
ELISA: 1:5,000-1:10,000
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Fig1: ICC staining FGF21 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining FGF21 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-FGF21 antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded rat stomach tissue using anti-FGF21 antibody. Counter stained with hematoxylin.
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