Anti-TGFBR3 antibody [H11-C5]

Anti-TGFBR3 antibody [H11-C5]

• 概述

• 产品描述A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors. TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.2.
• 产品名称Anti-TGFBR3 antibody [H11-C5]
• 分子量93 kDa
• 种属反应性Human,Mouse
• 验证应用WB
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG2b
• 纯化方式Protein A purified.
• 亚细胞定位Secreted, cell membrane.
• 其它名称
  • Beta glycan antibody
  • Betaglycan antibody
  • Betaglycan proteoglycan antibody
  more

• 应用

  WB: 1:500-1:2,000

•  

  

  Fig1: Western blot analysis of TGFBR3 on human TGFBR3 recombinant protein using anti-TGFBR3 antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of TGFBR3 on different cell lysate using anti-TGFBR3 antibody at 1/1,000 dilution.
  Positive control:
  Line1:Jurkat Line2:HeLa Line3:MCF-7 Line4:F9 Line5:SK-N-SH Line6:NIH3T3

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！