Anti-BDH1 antibody [C3-A5]

Anti-BDH1 antibody [C3-A5] 

• 概述

• 产品描述BDH1 (3-hydroxybutyrate dehydrogenase, type 1), also known as BDH or SDR9C1, is a 343 amino acid protein that localizes to the mitochondrial matrix and belongs to the short-chain dehydrogenases/reductases (SDR) family. Existing as a homotetramer, BDH1 functions to catalyze the NAD+-dependent interconversion of (R)-3-hydroxybutanoate and acetoacetate, a reaction that is allosterically activated by phosphatidylcholine. As both (R)-3-hydroxybutanoate and acetoacetate are two major ketone bodies produced during fatty acid catabolism, BDH1 plays an important role in the metabolic degradation of fatty acids. The gene encoding BDH1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
• 产品名称Anti-BDH1 antibody [C3-A5]
• 分子量45 kDa
• 种属反应性Human,Mouse
• 验证应用WB,IHC-P
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Mitochondrion matrix.
• 其它名称
  • 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) antibody
  • 3-hydroxybutyrate dehydrogenase antibody
  • BDH antibody
  more

• 应用

  WB: 1:500-1:1,000
  IHC-P: 1:50-1:200

•  

  

  Fig1: Western blot analysis of BDH1 on HepG2 and NIH/3T3 cell lysate using anti-BDH1 antibody at 1/1,000 dilution.

   

  

  Fig2: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-BDH1 antibody. Counter stained with hematoxylin.

   

  

  Fig3: Immunohistochemical analysis of paraffin-embedded human colorectal cancer tissue using anti-BDH1 antibody. Counter stained with hematoxylin.

   

  

  Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-BDH1 antibody. Counter stained with hematoxylin.

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