Anti-CCT2 antibody [C4-B5]

Anti-CCT2 antibody [C4-B5]

• 概述

• 产品描述The protein TCP-1 (t complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 α, β, γ, δ, ε, ζ, η and θ, each encoded by a different gene. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
• 产品名称Anti-CCT2 antibody [C4-B5]
• 分子量54 kDa
• 种属反应性Human,Mouse,Rat,Monkey
• 验证应用WB,FC
• 抗体类型小鼠单抗
• 免疫原Recombinant protein
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度2 mg/mL.
• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
• 存储缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
• 亚型IgG1
• 纯化方式Protein A purified.
• 亚细胞定位Cytoplasm.
• 其它名称
  • 99D8.1 antibody
  • CCT 2 antibody
  • CCT beta antibody
  more

• 应用

  WB: 1:500-1:1,000
  FC: 1:100-1:200

•  

  

  Fig1: Western blot analysis of TCP1 beta on human TCP1 beta recombinant protein using anti- TCP1 beta antibody at 1/1,000 dilution.

   

  

  Fig2: Western blot analysis of TCP1 beta on different cell lysates using anti- TCP1 beta antibody at 1/1,000 dilution.
  Positive control:
  Lane 1: Hela
  Lane 2: MCF-7
  Lane 3: Jurkat
  Lane 4: T47D
  Lane 5: K562
  Lane 6: A431
  Lane 7: NIH/3T3
  Lane 8: PC-12
  Lane 9: Cos7

   

  

  Fig3: Flow cytometric analysis of NIH/3T3 cells with TCP1 beta antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red).

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