Anti-OCT-4 antibody
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概述
- 产品描述Octamer transcription factor-4 (Oct-4) is a homeodomain transcription factor in the POU transcription factor family that specifically binds to the octamer motif (5'-ATTTCAT-3') (1). It is critical for early embryogenesis and for embryonic stem cell pluripotency, expressed mainly in the developing brain (1). OCT4 is a master regulator that affects the fate of pluripotent stem cells and germ cell precursors (2). For instance, the downregulation of Oct-4 triggers embryonic stem cell differentiation, simultaneous with gastrulation (3). It is also used as a marker for germ cell tumor diagnosis (4).
- 产品名称Anti-OCT-4 antibody
- 分子量45kDa
- 种属反应性Human
- 验证应用WB,IHC-P,FC,IP
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20 ℃. Stable for 12 months from date of receipt
- 存储缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Tissue culture supernatant
- 亚细胞定位Cytoplasm, Nucleus
- 其它名称
- Octamer binding transcription factor 4 antibody
- MGC22487 antibody
- Oct 3 antibody
more
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应用
WB: 1:1,000
IP: 1:10-100
IHC-P: 1:100
FC: 1:10-100
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Fig1: Western blot analysis on (A) Seminoma, (B) NCCIT, and (C) HeLa cell lysates using anti-Oct-4
Fig2: Immunohistochemical staining of paraffin-embedded human ovarian dysgerminoma using anti-Oct-4 RabMAb.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
