Anti-TMEM119 antibody
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概述
- 产品描述Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts . May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).
- 产品名称Anti-TMEM119 antibody
- 分子量Predicted band size: 29 kDa.
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthetic peptide within human Transmembrane protein 119 aa 120-170.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane.
- 其它名称
- OBIF antibody
- Osteoblast induction factor antibody
- PSEC0199 antibody
more
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Fig1: Western blot analysis of TMEM119 on SHSY5Y cell lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody () was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.
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