Anti-Cathepsin B antibody
-
概述
- 产品描述Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis.
- 产品名称Anti-Cathepsin B antibody
- 分子量38 kDa
- 种属反应性Human
- 验证应用WB,ICC
- 抗体类型兔多抗
- 免疫原Synthetic peptide (KLH-coupled) within human Cathepsin B C-terminal.
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Secreted
- 数据链接P07858 Human
- 其它名称
- Amyloid precursor protein secretase antibody
- APP secretase antibody
- APPS antibody
more
-
应用
WB: 1:500-1:1000
ICC: 1:200
-
Fig1: Western blot analysis on cell lysates using anti- Cathepsin B rabbit polyclonal antibodies.
Fig2: ICC staining Cathepsin B in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!