Anti-Geminin antibody

Anti-Geminin antibody

• 概述

• 产品描述Geminin is a nuclear protein that is present in most eukaryotics and highly conserved across species. Numerous functions have been elucidated for Geminin including roles in metazoan cell cycle, cellular proliferation, cell lineage commitment, and neural differentiation. During S phase, geminin is a negative regulator of DNA replication. In many cancer cell lines, inhibition of geminin by RNAi results in re-replication of portions of the genome, which leads to aneuploidy.
• 产品名称Anti-Geminin antibody
• 分子量24 kDa

• 种属反应性Human,Mouse, Rat

• 验证应用WB, ICC, FC

• 抗体类型兔多抗

• 免疫原peptide

• 偶联Non-conjugated

• 性能

• 形态Liquid

• 浓度1 mg/mL.

• 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

• 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• 亚型IgG

• 纯化方式Immunogen affinity purified.

• 亚细胞定位Nucleus, cytoplasm

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• 其它名称

  more

  • DNA replication inhibitor antibody

  • Gem antibody

  • GEMI_HUMAN antibody

• 应用

  WB: 1:500
  ICC: 1:50
  FC: 1:50-1:100

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  Fig1: Western blot analysis on Hela cell lysates using anti-Geminin rabbit polyclonal antibody.

   

  

  Fig2: ICC image of Geminin antibody stained NCCIT cells. The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.

   

  

  Fig3: ICC image of Geminin antibody stained F9 cells. The secondary antibody (green) was goat anti-rabbit IgG (H+L) FITC conjugated.

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