Anti-BCL2L1 antibody
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概述
- 产品描述Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis. Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2. It appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
- 产品名称Anti-BCL2L1 antibody
- 分子量~26kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,ICC,IHC-P
- 抗体类型兔多抗
- 免疫原peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 亚细胞定位Mitochondrion membrane, nucleus membrane, cytoplasm
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应用
WB: 1:500-1:1,000
ICC: 1:100-1:200
IHC-P: 1:200
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Fig1: Western blot analysis on A431 and K562 cell lysates using anti-BCL2L1rabbit polyclonal antibodies.
Fig2: Immunofluorescent staining of Hela cells using anti- BCL2L1 rabbit polyclonal antibody.
Fig3: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti- BCL2L1 rabbit polyclonal antibody.
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