Anti-IL-10Rα antibody
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概述
- 产品描述The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
- 产品名称Anti-IL-10Rα antibody
- 分子量63 kDa
- 种属反应性Human
- 验证应用WB, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human IL-10R alpha. AA range:462-511
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称IL10RA antibody; IL10R antibody; Interleukin-10 receptor subunit alpha antibody; IL-10 receptor subunit alpha antibody; IL-10R subunit alpha antibody; IL-10RA antibody; CDw210a antibody; Interleukin-10 receptor subunit 1 antibody; IL-10R subunit 1 antibody; IL-10R1 antibody; CD antigen CD210 antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using IL-10Rα Polyclonal Antibody
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