Anti-JNK1 antibody
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概述
- 产品描述Brain-derived neurotrophic factor, also known as BDNF, is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.
- 产品名称Anti-JNK1 antibody
- 分子量48/54 kDa
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种属反应性Human,Mouse,Rat,Zebrafish
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验证应用WB,ICC,IHC-P,FC
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抗体类型兔多抗
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免疫原peptide
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偶联Non-conjugated
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性能
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形态Liquid
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浓度1 mg/mL.
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存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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亚型IgG
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纯化方式Immunogen affinity purified
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亚细胞定位Secreted
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其它名称
more
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Abrineurin antibody
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ANON2 antibody
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BDNF antibody
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应用
WB: 1:500
ICC: 1:200
IHC-P: 1:200
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Fig1: Western blot analysis of JNK1 on different cell lysates using anti-JNK1 antibody at 1/1,000 dilution.
Positive control:
Lane 1: K562
Lane 2: PC-12
Lane 3: Hela
Fig2: ICC staining of BNDF in A172 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining of BNDF in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: ICC staining of BNDF in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig5: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Fig6: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Fig7: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-BDNF antibody. Counter stained with hematoxylin.
Fig8: Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-BDNF antibody. Counter stained with hematoxylin.
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