Anti-Integrin α4 antibody
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概述
- 产品描述The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
- 产品名称Anti-Integrin α4 antibody
- 分子量120 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA4. AA range:571-620
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- ITGA4 antibody; CD49D antibody; Integrin alpha-4 antibody; CD49 antigen-like family member D antibody; Integrin alpha-IV antibody; VLA-4 subunit alpha antibody; CD49d antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of K562 cells using Integrin α4 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-lymph, antibody was diluted at 1:100
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