Anti-Lambda 5 antibody
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概述
- 产品描述The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-Lambda 5 antibody
- 分子量23 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGLL1. AA range:151-200
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- IGLL1 antibody; IGL1 antibody; Immunoglobulin lambda-like polypeptide 1 antibody; CD179 antigen-like family member B antibody; Ig lambda-5 antibody; Immunoglobulin omega polypeptide antibody; Immunoglobulin-related protein 14.1 antibody; CD179b antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of KB cells using Lambda 5 Polyclonal Antibody.. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded human-lymph, antibody was diluted at 1:100
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