Anti-Myosin VI antibody
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概述
- 产品描述This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- 产品名称Anti-Myosin VI antibody
- 分子量149 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from Myosin VI . at AA range: 40-120
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- MYO6 antibody; KIAA0389 antibody; Unconventional myosin-VI antibody; Unconventional myosin-6 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of extracts from Jurkat cells, using Myosin VI Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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