Anti-UBE2A/B antibody
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概述
- 产品描述The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
- 产品名称Anti-UBE2A/B antibody
- 分子量17 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the C-terminal region of human UBE2A/B.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- UBE2A antibody; RAD6A antibody; Ubiquitin-conjugating enzyme E2 A antibody; RAD6 homolog A antibody; HR6A antibody; hHR6A antibody; Ubiquitin carrier protein A antibody; Ubiquitin-protein ligase A antibody; UBE2B antibody; RAD6B antibody; Ubiquitin-conjugating enzyme E2 B antibody;RAD6 homolog B antibody; HR6B antibody; hHR6B antibody; Ubiquitin carrier protein B antibody; Ubiquitin-conjugating enzyme E2-17 kDa antibody; Ubiquitin-protein ligase B antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-300
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Fig1: Western Blot analysis of extracts from Jurkat cells, using UBE2A/B Polyclonal Antibody.. Secondary antibody（catalog#：HA1001) was diluted at 1:20000
Fig2: Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100
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