Anti--Smad1/5/9 antibody
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概述
- 产品描述The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
- 产品名称Anti-Smad1/5/9 antibody
- 分子量56 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Smad1/5/9. AA range:10-59
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SMAD1 antibody; BSP1 antibody; MADH1 antibody; MADR1 antibody; Mothers against decapentaplegic homolog 1 antibody; MAD homolog 1 antibody; Mothers against DPP homolog 1 antibody; JV4-1 antibody; Mad-related protein 1 antibody; SMAD family member 1 antibody; SMAD 1 antibody; Smad1 antibody; hSMAD1 antibody; Transforming growth factor-beta-signaling protein antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using Smad1/5/9 Polyclonal Antibody diluted at 1：500
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