Anti-Zhangfei antibody
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概述
- 产品描述Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells. miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD. Belongs to the bZIP family. ATF subfamily. Contains 1 bZIP domain. subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1. subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity. tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
- 产品名称Anti-Zhangfei antibody
- 分子量26 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IHC-P,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 其它名称
- CREBZF antibody; ZF antibody; CREB/ATF bZIP transcription factor antibody; Host cell factor-binding transcription factor Zhangfei antibody; HCF-binding transcription factor Zhangfei antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
