Anti-VPS72 antibody
-
概述
- 产品描述The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
- 产品名称Anti-VPS72 antibody
- 分子量41 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human VPS72. AA range:131-180
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified
- 其它名称
- VPS72 antibody; TCFL1 antibody; YL1 antibody; Vacuolar protein sorting-associated protein 72 homolog antibody; Protein YL-1 antibody; Transcription factor-like 1 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
-
Fig1: Western blot analysis of 293T lysis using VPS72 antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog#:HA1001) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!