Anti-PAK5 antibody
-
概述
- 产品描述The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
- 产品名称Anti-PAK5 antibody
- 分子量80 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human PAK7. AA range:661-710
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- PAK7 antibody; KIAA1264 antibody; PAK5 antibody; Serine/threonine-protein kinase PAK 7 antibody; p21-activated kinase 5 antibody; PAK-5 antibody; p21-activated kinase 7 antibody; PAK-7 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
-
Fig1: Western Blot analysis of various cells using PAK5 Polyclonal Antibody
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!