Anti-GnRH-R antibody
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概述
- 产品描述This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gen
- 产品名称Anti-GnRH-R antibody
- 分子量37 kDa
- 种属反应性Human,Mouse
- 验证应用WB,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human GNRHR. AA range:41-90
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称GNRHR antibody; GRHR antibody; Gonadotropin-releasing hormone receptor antibody; GnRH receptor antibody; GnRH-R antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
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