Anti-HPK1 antibody
-
概述
- 产品描述catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 CNH domain. Contains 1 protein kinase domain. subunit:Interacts with MAP3K1. tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.
- 产品名称Anti-HPK1 antibody
- 分子量91 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称MAP4K1 antibody; HPK1 antibody; Mitogen-activated protein kinase kinase kinase kinase 1 antibody; Hematopoietic progenitor kinase antibody; MAPK/ERK kinase kinase kinase 1 antibody; MEK kinase kinase 1 antibody; MEKKK 1 antibody;
-
-
Fig1: Western Blot analysis of various cells using HPK1 Polyclonal Antibody diluted at 1:1000
Fig2: Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4°,overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!