Anti-Girdin antibody
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概述
- 产品描述This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- 产品名称Anti-Girdin antibody
- 种属反应性Human,Mouse
- 验证应用IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Girdin. AA range:1383-1432
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CCDC88A antibody; APE antibody; GRDN antibody; KIAA1212 antibody; Girdin antibody; Akt phosphorylation enhancer antibody; APE antibody; Coiled-coil domain-containing protein 88A antibody; G alpha-interacting vesicle-associated protein antibody; GIV antibody; Girders of actin filament antibody; Hook-related protein 1 antibody; HkRP1 antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
