Anti-KCNQ4 antibody
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概述
- 产品描述The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-KCNQ4 antibody
- 分子量80 kDa
- 种属反应性Human, Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human KCNQ4. AA range:644-693
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称KCNQ4 antibody; Potassium voltage-gated channel subfamily KQT member 4 antibody; KQT-like 4 antibody; Potassium channel subunit alpha KvLQT4 antibody; Voltage-gated potassium channel subunit Kv7.4 antibody;
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Fig1: Western Blot analysis of various cells using KCNQ4 Polyclonal Antibody
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