Anti-MARCH1 Polyclonal antibody
-
概述
- 产品描述MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al. 2004
- 产品名称Anti-MARCH1 Polyclonal Antibody
- 分子量32 kDa
- 种属反应性Human
- 验证应用IHC-P,WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human 40603.
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称MARCH1 antibody; RNF171 antibody; E3 ubiquitin-protein ligase MARCH1 antibody; Membrane-associated RING finger protein 1 antibody; Membrane-associated RING-CH protein I antibody; MARCH-I antibody; RING finger protein 171 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
