Anti-Histone deacetylase 9 antibody
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概述
- 产品描述Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 9 encoded by HDAC9 has sequence homology to members of the histone deacetylase family. HDAC9 is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
- 产品名称Anti-Histone deacetylase 9 antibody
- 分子量110 kDa
- 种属反应性Human
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human HDAC9. AA range:1017-1066
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称Histone deacetylase 9 antibody; HD9 antibody; Histone deacetylase 7B antibody; HD7 antibody; HD7b antibody; Histone deacetylase-related protein antibody; MEF2-interacting transcription repressor MITR antibody; HDAC9 antibody; HDAC7 antibody; HDAC7B antibody; HDRP antibody; KIAA0744 antibody; MITR antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using Histone deacetylase 9 Polyclonal Antibody diluted at 1:1000
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!