Anti-GBDR1 antibody
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概述
- 产品描述Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. pathway:Protein modification; protein ubiquitination. Contains 1 STI1 domain. Contains 1 ubiquitin-like domain. Contains 2 UBA domains. subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain. tissue specificity:Ubiquitous.
- 产品名称Anti-GBDR1 antibody
- 分子量45 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称UBAC1 antibody; GBDR1 antibody; KPC2 antibody; UBADC1 antibody; Ubiquitin-associated domain-containing protein 1 antibody; UBA domain-containing protein 1 antibody; E3 ubiquitin-protein ligase subunit KPC2 antibody; Glialblastoma cell differentiation-related protein 1 antibody; Kip1 ubiquitination-promoting com antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of various cells using GBDR1 Polyclonal Antibody diluted at 1:500
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