Anti-LAMP2a antibody
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概述
- 产品描述Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.
- 产品名称Anti-LAMP2a antibody
- 种属反应性Human,Mouse
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原Synthetic peptide within C-terminal human LAMP2a.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Plasma membrane. Endosome. Lysosome.
- 其它名称CD107 antigen-like family member B antibody
CD107b antibody
LAMP 2 antibody
Lamp 2a antibody
LAMP-2 antibody
LAMP2 antibody
LAMP2_HUMAN antibody
Lysosome-associated membrane glycoprotein 2 antibody
Lysosome-associated membrane protein 2 antibody
more
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应用
WB: 1:500
IHC-P: 1:50-1:200
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Fig1: Western blot analysis of LAMP2a on mouse placenta tissue lysates using anti-LAMP2a antibody at 1/1,000 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded human prostate tissue using anti-LAMP2a antibody. Counter stained with hematoxylin.
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