Anti-LT-β antibody
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概述
- 产品描述Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e. g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 产品名称Anti-LT-β antibody
- 分子量22 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human TNFC. AA range:181-230
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称LTB antibody; TNFC antibody; TNFSF3 antibody; Lymphotoxin-beta antibody; LT-beta antibody; Tumor necrosis factor C antibody; TNF-C antibody; Tumor necrosis factor ligand superfamily member 3 antibody;
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应用
WB: 1:500-1:2000
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using LT-β Polyclonal Antibody
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