Anti-ATP7B antibody
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概述
- 产品描述This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
- 产品名称Anti-ATP7B antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human ATP7B. AA range:161-210
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ATP7B antibody; PWD antibody; WC1 antibody; WND antibody; Copper-transporting ATPase 2 antibody; Copper pump 2 antibody; Wilson disease-associated protein antibody;
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应用
IHC-P: 1:100-1:300
IF: 1:100-1:500
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!