Anti-Atg4D antibody
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概述
- 产品描述Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
- 产品名称Anti-Atg4D antibody
- 分子量52 kDa
- 种属反应性Human
- 验证应用WB, IHC-P
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from the Internal region of human Atg4D.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ATG4D antibody; APG4D antibody; AUTL4 antibody; Cysteine protease ATG4D antibody; AUT-like 4 cysteine endopeptidase antibody; Autophagin-4 antibody; Autophagy-related cysteine endopeptidase 4 antibody; Autophagy-related protein 4 homolog D antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
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Fig1: Western Blot analysis of Colo using Antibody diluted at 1:1000. Secondary antibody(catalog#:HA1001) was diluted at 1:20000
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