Anti-NPL4 antibody
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概述
- 产品描述domain:Binds ubiquitinated proteins via its RanBP2-type zinc finger. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. pathway:Protein degradation; proteasomal ubiquitin-dependent pathway. Belongs to the NPL4 family. Contains 1 RanBP2-type zinc finger. subcellular location:Associated with the endoplasmic reticulum and nuclear. subunit:Heterodimer with UFD1L. The heterodimer binds ubiquitinated proteins. The heterodimer binds to VCP and inhibits Golgi membrane fusion. tissue specificity:Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver.
- 产品名称Anti-NPL4 antibody
- 分子量66 kDa
- 种属反应性Human,Rat,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human protein . at AA range: 270-350
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
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特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
