Anti-Actinin-α2/3 antibody
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概述
- 产品描述Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
- 产品名称Anti-Actinin-α2/3 antibody
- 分子量103 kDa
- 种属反应性Human, Mouse, Rat
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Actinin alpha-2/3. AA range:31-80
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称ACTN2 antibody; Alpha-actinin-2 antibody; Alpha-actinin skeletal muscle isoform 2 antibody; F-actin cross-linking protein antibody; ACTN3 antibody; Alpha-actinin-3 antibody; Alpha-actinin skeletal muscle isoform 3 antibody; F-actin cross-linking protein antibody;
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应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
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Fig1: Western Blot analysis of various cells using Actinin-α2/3 Polyclonal Antibody
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!