Anti-Cadherin-20 antibody
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概述
- 产品描述This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
- 产品名称Anti-Cadherin-20 antibody
- 种属反应性Human,Mouse,Rat
- 验证应用IHC-P,IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称CDH20 antibody; CDH7L3 antibody; Cadherin-20 antibody;
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应用
IHC-P: 1:100-1:300
IF: 1:100-1:500
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