Anti-LIGO1 antibody
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概述
- 产品描述Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. PTM:N-glycosylated. Contains predominantly high-mannose glycans. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 13 LRR (leucine-rich) repeats. subunit:Homotetramer. Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19. tissue specificity:Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.
- 产品名称Anti-LIGO1 antibody
- 分子量68 kDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原Synthesized peptide derived from human protein . at AA range: 370-450
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
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