Anti-Cleaved-Caspase-4/5 p20 (D270/D311) antibody
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概述
- 产品描述This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
- 产品名称Anti-Cleaved-Caspase-4/5 p20 (D270/D311) antibody
- 分子量47/22 kDa
- 种属反应性Human
- 验证应用WB
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human Caspase 4/5. AA range:221-270
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 亚细胞定位Cytosol.
- 其它名称CASP4 antibody
ICH2 antibody
Caspase-4 antibody
CASP-4 antibody
ICE(rel)-II antibody
Protease ICH-2 antibody
Protease TX antibody
CASP5 antibody
ICH3 antibody
Caspase-5 antibody
CASP-5 antibody
ICE(rel)-III antibody
Protease ICH-3 antibody
Protease TY antibody
more
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Fig1: Western blot analysis of Caspase 4/5 (p20, Cleaved-Asp270/Asp311) Antibody. The lane on the right is blocked with the Caspase 4/5 (p20, Cleaved-Asp270/Asp311) peptide.
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