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| 别名: | Integrin beta-1/CD29 | ||
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| 适用物种: | Human,Mouse | ||
| 验证应用: | WB,IHC-P,FC | ||
| 种属: | 兔多抗 | ||
| 储存条件: | -20℃ | ||
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| 货号 | 规格 | 可用库存 | 销售价(RMB) | 您的折扣价(RMB) | 购买数量 |
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| 密度: | |
| 储存条件: | -20℃ |
Anti-Integrin beta-1/CD29 antibody
产品描述Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90?kDa to 160?kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.
产品名称Anti-Integrin beta-1/CD29 antibody
分子量100 kDa
种属反应性Human,Mouse
验证应用WB,IHC-P,FC
抗体类型兔多抗
免疫原peptide
偶联Non-conjugated
形态Liquid
浓度1 mg/mL.
存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
存储缓冲液1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
亚型IgG
纯化方式Peptide affinity purified
亚细胞定位Cell membrane, cytoplasm
其它名称
WB: 1:500-1:1,000
FC: 1:100
IHC-P: 1:200
Fig1: Western blot analysis of CD29 on different cell lysates using anti-CD29 antibody at 1/1000 dilution.
Positive control:
Lane 1: Human liver
Lane 2: Human kidney
Lane 3: NIH/3T3
Lane 4: A172
Lane 5: Hela
Fig2: Immunohistochemical analysis of paraffin-embedded human liver carcinoma tissue using anti-CD29 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-CD29 antibody. Counter stained with hematoxylin.
Fig4: Flow cytometric analysis of HepG2 cells with CD29 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti rabbit IgG (FITC) was used as the secondary antibody.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
