Anti-Thrombin light chain antibody
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概述
- 产品描述Thrombin is an active enzyme in the earliest steps of the blood clot formation, generated from its circulating inactive precursor prothrombin. Thrombin is a glycoprotein formed by two peptides chains of 36 and 259 amino acids linked by disulfure bonds. Three important sites have been identified on the surface of the enzyme: The catalytic site that confers to the molecule its serine protease activity, the exosite one responsible for the binding of the substrate (fibrinogen or thrombin receptor) and the exosite two responsible for the binding of antithrombin III and inactivation of thrombin. Gamma Thrombin is a proteolyzed form of Alpha Thrombin. Gamma Thrombin consists of four chains (A, B1, B5, B4) with a disulfide link between the A peptide and the B5 peptide.
- 产品名称Anti-Thrombin light chain antibody
- 分子量4/64 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,Guinea Pig
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human Thrombin light chain 328-363/622
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Secreted, extracellular space.
- 其它名称coagulation factor II
prothrombin
F2
Cf-2
Cf2
FII
F 2
coagulation factor II (thrombin)
Coagulation factor II
Coagulation factor II precursor
F2
Factor II
Factor-II
Prothrombin
prothrombin B-chain
PT
serine protease
THRB
THRB_HUMAN
Thrombin
Thrombin light chain.
more
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Fig1: Protein: liver(mouse) lysate at 40ug;
Primary: rabbit Anti-Thrombin light chain at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 64 kD
Observed band size: 64 kD
Fig2: Protein: placenta(mouse) lysate at 40ug;
Primary: rabbit Anti-Thrombin light chain at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 64 kD
Observed band size: 64 kD
Fig3: Sample: placenta (Mouse) Lysate at 40 ug
Primary: Anti-Thrombin light chainat 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 64 kD
Observed band size: 64 kD
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!