Anti-OMA1 antibody
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概述
- 产品描述Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
- 产品名称Anti-OMA1 antibody
- 分子量60 KDa
- 种属反应性Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Zebrafish,Cat
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human OMA1 401-500/524
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Mitochondrion membrane.
- 其它名称2010001O09Rik
DAB1
FLJ33782
Metalloendopeptidase OMA1
Metalloendopeptidase OMA1, mitochondrial
Metalloprotease-related protein 1
mitochondrial
MPRP 1
MPRP-1
MPRP1
OMA1
OMA1 homolog zinc metallopeptidase
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
OMA1 zinc metallopeptidase
OMA1 zinc metallopeptidase homolog
OMA1_HUMAN
Overlapping activity with M-AAA protease
Overlapping with the m-AAA protease 1 homolog
peptidase
YKR087C
Zinc metallopeptidase OMA1
ZMPOMA1.
more
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Fig1: Sample:
TT Cell (Human) Lysate at 40 ug
Primary: Anti- OMA1 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 55 kD
Fig2: Sample: Heart (Mouse) Lysate at 40 ug
Primary: Anti- OMA1 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 55 kD
Fig3: Sample: Kidney (Mouse) Lysate at 40 ug
Primary: Anti- OMA1 (at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 55 kD
Fig4: Sample: Heart (Rat) Lysate at 40 ug
Primary: Anti- OMA1 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kD
Observed band size: 55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
