Anti-HIP55 antibody
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概述
- 产品描述Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
- 产品名称Anti-HIP55 antibody
- 分子量55 KDa
- 种属反应性Human,Mouse
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human HIP55 201-300/430
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
- 亚型IgG
- 纯化方式affinity purified by Protein A
- 亚细胞定位Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Cortical cytoskeleton. Associates with lamellipodial actin.
- 其它名称ABP1
Actin-binding protein 1
Cervical mucin associated protein
Cervical mucin-associated protein
Cervical SH3P7
CMAP
Dbnl
DBNL_HUMAN
Drebrin F
drebrin like
Drebrin like protein
Drebrin-F
Drebrin-like protein
HIP 55
HIP-55
HPK1 interacting protein of 55 kDa
HPK1-interacting protein of 55 kDa
SH3 domain containing protein 7
SH3 domain-containing protein 7
SH3P7
Src Homology 3 Domain Containing Protein
src homology 3 domain containing protein HIP.
more
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Fig1: Protein:
lymph node(mouse) lyates at 40ug;
spleen(mouse) lyates at 40ug;
Primary: Rabbit Anti-HIP55 at 1:300;
Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000;
Predicted band size:55 kD
Observed band size:55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
