Anti-Dynamin 1 antibody
-
概述
- 产品描述Members of the Dynamin family, including Dynamin I and Dynamin II, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Both dynamin proteins contain SH3 and proline-rich domains that mediate interactions between the dynamins and effectors of their GTPase activity). The interactions with these effectors, which include microtubules, acidic phospholipids and SH3 domain-containing proteins, are required for rapid endocytosis. Dynamin I appears to be recruited to clathrin coated pits by SH3 domain interaction with amphiphysin, a protein highly expressed in brain.
- 产品名称Anti-Dynamin 1 antibody
- 分子量97 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用WB,IHC-P
- 抗体类型兔多抗
- 免疫原Recombinant protein within human Dynamin 1 aa 575-750.
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Protein affinity purified.
- 亚细胞定位Cytoplasm. Cytoskeleton.
- 其它名称B dynamin antibody
D100 antibody
DNM 1 antibody
DNM antibody
DNM1 antibody
DYN1_HUMAN antibody
Dynamin antibody
Dynamin-1 antibody
Dynamin1 antibody
more
-
应用
WB: 1:500-1:1,000
IHC-P: 1:50-1:200
-
Fig1: Western blot analysis of Dynamin 1 on mouse brain tissue lysate using anti-Dynamin 1 antibody at 1/500 dilution.
Fig2: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.
Fig3: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.
Fig4: Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-Dynamin 1 antibody. Counter stained with hematoxylin.
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
