Anti-Splicing factor 1 antibody
-
概述
- 产品描述This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
- 产品名称Anti-Splicing factor 1 antibody
- 分子量68 kDa
- 种属反应性Human, Mouse
- 验证应用WB, IHC-P, IF
- 抗体类型兔多抗
- 免疫原The antiserum was produced against synthesized peptide derived from human SF1. AA range:48-97
- 偶联Non-conjugated
-
性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 亚型IgG
- 纯化方式Immunogen affinity purified.
- 其它名称
- SF1 antibody; ZFM1 antibody; ZNF162 antibody; Splicing factor 1 antibody; Mammalian branch point-binding protein antibody; BBP antibody; mBBP antibody; Transcription factor ZFM1 antibody; Zinc finger gene in MEN1 locus antibody; Zinc finger protein 162 antibody;
-
应用
WB: 1:500-1:2000
IHC-P: 1:100-1:300
IF: 1:100-1:500
-
Fig1: Western Blot analysis of various cells using Splicing factor 1 Polyclonal Antibody diluted at 1：500
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
