Anti-Fibrillarin antibody
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概述
- 产品描述Fibrillarin is a widely occurring, basic, nonhistone protein that is localized exclusively in the fibrillar region of the nucleolus, including both the dense fibrillar and the fibrillar center regions. Fibrillarin is also expressed in HeLa cells, 3T3 cells, and human peripheral blood lymphocytes. In metaphase and anaphase, fibrillarin is found on putative chromosomal nucleolar regions (NORs). During telophase, fibrillarin is an early marker for the site of the newly forming nucleolus. The structure of fibrillarin includes an RNA-binding domain and an RNP consensus sequence, which is consistent with the association of fibrillarin with the U3 small nucleolar RNA. Fibrillarin is involved in processing rRNA transcripts in the nucleolus.
- 产品名称Anti-Fibrillarin antibody
- 分子量34 kDa
- 种属反应性Human,Mouse
- 验证应用WB,FC
- 抗体类型兔多抗
- 免疫原Synthetic peptide of C-terminal human Fibrillarin.
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified.
- 亚细胞定位Nucleus.
- 其它名称34 kD nucleolar scleroderma antigen antibody
34 kDa nucleolar scleroderma antigen antibody
Fbl antibody
FBRL_HUMAN antibody
FIB antibody
FIB1 antibody
FLRN antibody
Histone-glutamine methyltransferase antibody
Nop1p antibody
RNA U3 small nucleolar interacting protein 1 antibody
RNU3IP1 antibody
rRNA 2' O methyltransferase fibrillarin antibody
rRNA 2'-O-methyltransferase fibrillarin antibody
more
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应用
WB: 1:500-1:1,000
FC: 1:50-1:100
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Fig1: Western blot analysis of Fibrillarin on different cell lysates using anti-Fibrillarin antibody at 1/1,000 dilution.
Positive control:
Lane 1: Hela
Lane 2: HepG2
Lane 3: 293T
Lane 4: NIH-3T3
Fig2: Flow cytometric analysis of HL-60 cells with Fibrillarin antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
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