Anti-Angiopoietin-like 4 antibody
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概述
- 产品描述Angiopoietin-like 4 is a protein that in human is encoded by the ANGPTL4 gene. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2, HFARP, PGAR, or FIAF but has been renamed ANGPTL4. This gene is induced under hypoxic (low oxygen) condition in various cell types and is the target of Peroxisome proliferator-activated receptors. The encoded protein is a serum hormone directly involved in regulating lipid metabolism. The native full length ANGPTL4 can form higher order structures via intermolecular disulfide bonds. The N-terminal region of ANGPTL4 (nANGPTL4) is responsible for its assembly. The full length ANGPTL4 undergoes proteolytic cleavage at the linker region, releasing nANGPTL4 and the monomeric C-terminal portion of ANGPTL4 (cANGPTL4). The nANGPTL4 and cANGPTL4 have different biological functions. Monoclonal antibodies targeting the nANGPTL4 and cANGPTL4 have been developed to distinguish their functions.
- 产品名称Anti-Angiopoietin-like 4 antibody
- 分子量45 KDa
- 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Rabbit
- 验证应用WB
- 抗体类型兔多抗
- 免疫原KLH conjugated synthetic peptide derived from human ANGPTL4/ARP4 331-406/406
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 亚型IgG
- 纯化方式Affinity purified by Protein A
- 亚细胞定位Secreted. Secreted, extracellular space, extracellular matrix.
- 其它名称Angiopoietin like 4
Angiopoietin related protein 4
Angiopoietin-like protein 4
Angiopoietin-related protein 4
ANGL4_HUMAN
ANGPT L2
ANGPT L4
ANGPTL2
ANGPTL4
ARP4
Fasting induced adipose factor
FIAF
Hepatic angiopoietin related protein
Hepatic fibrinogen/angiopoietin related protein
Hepatic fibrinogen/angiopoietin-related protein
HFARP
NL2
Peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin related protein antibody PGAR
pp1158
PPARG angiopoietin related protein
PSEC0166
Weakly similar to angiopoietin 1 [H.sapiens].
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Fig1: Sample:
Placenta (Mouse) Lysate at 40 ug
Liver (Mouse) Lysate at 40 ug
Muscle (Rat) Lysate at 40 ug
Primary: Anti-Angiopoietin-like 4 at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 45 kD
Observed band size: 55 kD
特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！
