Anti-Activin A Receptor Type IC antibody

Anti-Activin A Receptor Type IC antibody

• 概述

• 产品描述Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
• 产品名称Anti-Activin A Receptor Type IC antibody
• 分子量53 KDa
• 种属反应性Human,Mouse,Rat,Dog,Pig,Cow,Rabbit
• 验证应用WB,FC
• 抗体类型兔多抗
• 免疫原KLH conjugated synthetic peptide derived from human ACTRIC/Activin A Receptor Type IC 21-120/493
• 偶联Non-conjugated

• 性能

• 形态Liquid
• 浓度1 mg/mL.
• 存放说明Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
• 存储缓冲液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
• 亚型IgG
• 纯化方式affinity purified by Protein A
• 亚细胞定位Membrane; Single-pass type I membrane protein.
• 其它名称Activin A receptor, type IC
  Activin receptor like kinase 7
  Activin receptor type 1C precursor
  Activin receptor type IC
  Activin receptor type-1C
  Activin receptor-like kinase 7
  ACTR IC
  ACTR-IC
  ACTRIC
  ACV1C_HUMAN
  Acvr1c
  ACVRLK7
  ALK 7
  ALK-7
  ALK7.
  more

• 应用

  WB:1:500-2000
  FC:3μg/Test

•  

  

  Fig1: Sample:
  Heart (Mouse) Lysate at 40 ug
  Primary: Anti-Activin A Receptor Type IC ( at 1/1000 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 53 kD
  Observed band size: 53 kD

   

  

  Fig2: Sample:
  Placenta (Mouse) Lysate at 40 ug
  Primary: Anti-Activin A Receptor Type IC (at 1/1000 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 53 kD
  Observed band size: 53 kD

   

  

  Fig3: Sample:
  HepG2(Human) Cell Lysate at 30 ug
  Hela(Human) Cell Lysate at 30 ug
  Primary: Anti-Activin A Receptor Type IC at 1/1000 dilution
  Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
  Predicted band size: 53 kD
  Observed band size: 53 kD

   

  

  Fig4: Blank control: H9C2 (blue)
  Isotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:100 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 3μl in 100 μL1X PBS containing 0.5% BSA(green).

特别提示：本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！