Anti-KDM5B antibody
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概述
- 产品描述PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
- 产品名称Anti-KDM5B antibody
- 分子量179 kDa
- 种属反应性Human,Mouse,Rat
- 验证应用ICC,IHC-P
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
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性能
- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Nucleus.
- 其它名称Cancer/testis antigen 31 antibody
CT31 antibody
Histone demethylase JARID1B antibody
JARID1B antibody
Jumonji AT rich interactive domain 1B antibody
Jumonji/ARID domain-containing protein 1B antibody
Kdm5b antibody
KDM5B_HUMAN antibody
Lysine (K) specific demethylase 5B antibody
Lysine demethylase 5B antibody
Lysine specific demethylase 5B antibody
Lysine-specific demethylase 5B antibody
PLU-1 antibody
PLU1 antibody
PPP1R98 antibody
Protein phosphatase 1 regulatory subunit 98 antibody
PUT1 antibody
putative DNA/chromatin binding motif antibody
RBBP2H1A antibody
RBP2 like antibody
RBP2-H1 antibody
Retinoblastoma-binding protein 2 homolog 1 antibody
Retinoblastoma-binding protein 2 homolog 1A antibody
more
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应用
ICC: 1:100-1:500
IHC-P: 1:50-1:200
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Fig1: ICC staining KDM5B in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig2: ICC staining KDM5B in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig3: ICC staining KDM5B in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Fig4: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-KDM5B antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-KDM5B antibody. Counter stained with hematoxylin.
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