Anti-Osteopontin antibody
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概述
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- 产品描述Osteopontin (OPN), also designated bone sialoprotein 1, urinary stone protein, spp-1, Eta-1, nephropontin and uropontin, is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPN isolated from or secreted by various tissues ranges in molecular weight due to posttranslational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.
- 产品名称Anti-Osteopontin antibody
- 分子量32 kDa
- 种属反应性Human,Mouse
- 验证应用ICC,IHC-P,ELISA
- 抗体类型兔多抗
- 免疫原Peptide
- 偶联Non-conjugated
性能
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- 形态Liquid
- 浓度1 mg/mL.
- 存放说明Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 存储缓冲液1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- 亚型IgG
- 纯化方式Peptide affinity purified
- 亚细胞定位Secreted.
- 其它名称BNSP antibody
Bone sialoprotein 1 antibody
BSP I antibody
BSPI antibody
Early T lymphocyte activation 1 antibody
ETA 1 antibody
ETA1 antibody
MGC110940 antibody
Nephropontin antibody
OPN antibody
Osteopontin antibody
osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody
OSTP_HUMAN antibody
PSEC0156 antibody
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody
Secreted phosphoprotein 1 antibody
SPP 1 antibody
SPP-1 antibody
SPP1 antibody
SPP1/CALPHA1 fusion antibody
Urinary stone protein antibody
Uropontin antibody
more
应用
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ICC: 1:50-1:200
IHC-P: 1:50-1:200
ELISA: 1:5,000-1:10,000
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Fig1: ICC staining Osteopontin in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Fig2: ICC staining Osteopontin in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Osteopontin antibody. Counter stained with hematoxylin.
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Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Osteopontin antibody. Counter stained with hematoxylin.
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Fig5: Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Osteopontin antibody. Counter stained with hematoxylin.
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